Anti-obesity Supplements – A deep Analysis | Benefits | Side Effects | Market Survey


More than half of the people in the United States are overweight. Obesity, on the other hand, differs from being overweight in many ways. Individuals are termed obese if their weight is 20% (or 25% in women) or more over the maximum ideal height weight for their age and height. It is called morbid obesity if an adult is more than 100 pounds overweight.

Obesity can alternatively be defined as a BMI (body mass index) of more than 30 kg/m2. Those who have a BMI between 25 and 29.9 are overweight, but not obese. Diet and caloric intake are also discussed.

Weight loss is a common goal, and many people look for support in any way they can. It’s important to keep in mind that research on numerous supplements and herbal therapies is mixed. When it comes to some of the assertions, there isn’t a lot of evidence to back them up. Before trying any new medication, consult with your doctor.

If you’re looking for a weight reduction supplement, you should know that the FDA has taken action against several products containing prescription medicines that weren’t included on the label. You never know what you’ll get.

Unlike food and medications, supplements are not subject to FDA oversight. The Food and Drug Administration does not assess these supplements for safety or efficacy before they go on sale.

Anti-obesity Supplement

Weight-Loss Dietary Supplements Regulation

Dietary supplements, especially weight reduction supplements, are regulated by the FDA in the United States. Weight-loss supplements, like other dietary supplements, are not classified as pharmaceuticals by the FDA, unlike over-the-counter or prescription treatments. Dietary supplements don’t have to be approved by the FDA before they may be sold on the market. The producers of supplements are responsible for ensuring that their products are safe and that their label claims are accurate and true. An dangerous supplement may be taken off the market by the FDA, or the producer may be asked to recall it if necessary. Unsubstantiated weight-loss claims concerning a product can be subject to enforcement by the FDA and the Federal Trade Commission. Neither the FDA nor supplement producers are allowed to market dietary supplements to be used in the diagnosis, treatment, cure or prevention of any disease.

Rates of childhood obesity

About one in five American children are obese, according to the Centers for Disease Control and Prevention (CDC).

More Latino and African-American children are obese than those of any other race or ethnicity.

Rates of obesity among children ages 2 to 19 in the United States, as reported by the CDC, are as follows:

  • 24.2 percent of the population is non-Hispanic black.
  • 25.6 percent of the population is made up of Hispanics.
  • Among whites who aren’t Hispanics, 16.1% are
  • Non-Hispanic Asians comprise 8.7% of the population.

The National Health and Nutrition Examination Survey (NHANES) data from 1999 to 2016 was examined in a report published in Pediatrics. Over the past 15 years, the percentage of children aged 2 to 19 who are obese has increased from 29 percent to 35 percent, according to the survey. Obesity rates among toddlers ages 2 to 5 and adolescent females ages 16 to 19 rose sharply between 2015 and 2016, according to a new study. According to the Centers for Disease Control and Prevention, 41.5 percent of teenagers ages 16 to 19 were obese.

As in previous years, racial disparities persist: Hispanics and African-Americans are more likely to be obese than whites in practically every category of obesity. In addition to socioeconomic position, poorer people are more likely to be obese.

Body Mass Index (BMI)

Body Mass Index (BMI) is a screening tool used to assess weight issues in children. A person’s BMI is calculated by dividing their weight in kilograms by their height in meters squared. Children are considered obese if their BMI exceeds the 95th percentile for their age and gender (using the CDC sex-specific BMI-for-age growth charts). Doctors’ interpretation of BMI results in children, adolescents, and teens differs from that of adults, despite the fact that BMI is calculated in the same manner.

childhood obesity
Doctor measuring overweight boy in clinic

Using BMI, we can detect children who are gaining weight at an abnormally slow or rapid rate. BMI is calculated using a child’s height and weight, just as it is for adults. It is important to note, however, that a child’s age and gender can alter the amount of body fat he or she has.

What Leads to Weight Gain and Obesity?

Food intake, portion size and calorie content

Overconsumption of food and calories can lead to fat storage in the body. High-fat and high-sugar foodstuffs can make you overweight. You will gain weight if you don’t expend more calories than you consume.


A sedentary lifestyle, without appropriate exercise and proper diet, can increase the risk of becoming obese or overweight. Sedentary lifestyles can be exacerbated by the use of electronic devices, such as computers and mobile phones. The likelihood of weight problems can be reduced by including exercise into one’s everyday routine. A sedentary lifestyle, excessive food consumption, and poor food choices all contribute to weight gain. Sugary soft drinks and excessive alcohol consumption contribute to weight gain.


You may be more likely to be overweight or obese if you have a family history of obesity. Overweight children and adolescents are more likely to be obese adults as well, therefore family history is an important consideration. Eating habits and dietary preferences are often passed down through families, which can lead to weight gain.

Metabolic Rate

It is possible for people of same height and weight to have different metabolic rates. It takes longer for someone with a low metabolic rate to burn off the calories they consume. When it comes to maintaining a certain weight, people with low metabolic rates consume less calories than those who have high metabolic rates.

Medical conditions

Cushing’s syndrome, for example, can contribute to weight gain, as can arthritis or pain, which reduces one’s level of activity.


The following medicines have been shown to cause weight gain:

  • Glucocorticoids are drugs like prednisone and methylprednisolone that are called “steroids.”
  • Antipsychotic drugs like clozapine (Clozaril), olanzapine (Zyprexa), risperidone (Risperdal), and quetiapine (Seroquel) are often linked to weight gain.
  • A number of commonly prescribed antidepressants, including amitriptyline, mirtazapine, and paroxetine (Paxil) (Remeron).
  • Medications for epilepsy, diabetes, and high blood pressure can also cause weight gain.


Pregnancy can cause women to acquire weight that is difficult to lose. There are risks to the developing fetus if a pregnant woman diets or uses weight-loss medicines. Concerns concerning weight gain during pregnancy should be discussed with the patient’s physician.

Other elements have a role as well.

Other variables that lead to weight increase include socioeconomic, age and hormonal changes, smoking cessation and a lack of sleep, as well as stress.

Common Ingredients in Weight-Loss Dietary Supplements

There are many different substances in weight loss supplements. So it’s not unexpected that there’s a wide range of scientific research on these compounds. They may be based on animal and laboratory studies rather than clinical trials in some situations. However, in certain circumstances, studies supporting the usage of a given component are small in duration or low-quality. Research into the safety and efficacy of a given substance is nearly always required.

Study results can be difficult to understand because many weight-loss products contain many substances, making it impossible to separate each ingredient’s specific effects and anticipate the combined outcomes. There may be evidence for only one ingredient in a finished product, and there may be no evidence for an ingredient when it is mixed with other substances. As a result, weight-loss supplement dosages and levels of active components can vary substantially, and published studies do not always adequately define the product’s composition. The effectiveness of a treatment may also be evaluated using a variety of methods, some of which may be ineffective. All of these factors make it difficult to compare one study’s conclusions to another’s.

According to this information sheet, the safety and effectiveness of the most prevalent substances in weight-loss dietary supplements are described in greater detail in Table 1. The ingredients are listed alphabetically in the table and the text. There are times when dosage information is available. Because ingredients may not be standardized and many products contain unique blends of substances, the active chemicals and their concentrations may not be comparable among goods.

African mango (Irvingia gabonensis)It decreases leptin levels and inhibits adipogenesis.
Beta-glucansFaster digestion, longer satiety and slower glucose absorption are all benefits of this supplement.
Bitter orange (Citrus aurantium L.)As a modest appetite suppressant, it boosts energy expenditure and lipolysis. Synephrine has been proposed as the primary active ingredient in this formulation.
Caffeine (as added caffeine or from guarana, kola nut, yerba maté, or other herbs)Increases thermogenesis and fat oxidation by stimulating the central nervous system.
CalciumLipolysis increases, fat formation is reduced, and fat absorption is reduced.
Capsaicin and other capsaicinoidsReduces caloric intake and raises metabolic rate and oxidative phosphorylation of lipids
CarnitineIt enhances the oxidation of fatty acids.
ChitosanFat is trapped in the digestive system by this supplement.
ChromiumReduces appetite, decreases food intake, and decreases the desire to eat fat
Coleus forskohliiIt boosts fat-burning and lowers hunger. The active ingredient in question is forskolin.
Conjugated linoleic acidLipolysis increases, lipogenesis is reduced, and apoptosis is promoted in adipose tissue as a result
FucoxanthinSuppression of adipocyte differentiation and accumulation of lipids are two of the many effects.
Garcinia cambogia (hydroxycitric acid)Lipogenesis is inhibited, and food intake is reduced as a result. The active ingredient is hydroxycitric acid.
GlucomannanIt prolongs the time it takes for the stomach to empty, increasing feelings of fullness.
Green coffee bean extract (Coffea arabica, Coffea canephora, Coffea robusta)Fat formation and glucose metabolism are both inhibited by this supplement
Green tea (Camellia sinensis) and green tea extractIncreases fat oxidation and energy expenditure while decreasing lipogenesis and absorption.
Guar gumIncreases feelings of satiety by acting as a bulking agent in the gastrointestinal tract.
Hoodia (Hoodia gordonii)Suppresses hunger and lowers the amount of food consumed
ProbioticsGut microbiota changes, modifying nutritional and energy extraction from food, and altering energy expenditure, as a result of these changes.
PyruvateIt raises lipolysis and expenditure of energy.
Raspberry ketoneChanges the metabolism of fats and oils
Vitamin DIt has never been suggested; nonetheless, there is a correlation between a lack of vitamin D and an increased risk of obesity.
White kidney bean (Phaseolus vulgaris)It acts as a “starch blocker,” preventing the digestion and absorption of carbohydrates.
Yohimbe (Pausinystalia yohimbe)It has an effect on the adrenal glands. The active ingredient in question is yohimbine.

How Weight Loss Supplements Works

If you’re looking for weight-loss pills, your options are nearly endless. You might expect to see results like these if you use these supplements, according to the manufacturers.

  • Eat less to satisfy your hunger pangs (chickweed, bee pollen, fennel)
  • Prevent overeating by making you feel satisfied before you’ve even eaten anything (guar gum, psyllium)
  • Boost your metabolic rate (caffeine, guarana, synephrine, B-complex vitamins)
  • Reduce your body’s ability to store fat (green tea, hydrocitric acid, flax seed)
  • Ease yourself out of having your body absorb fat from the meals you consume (chondritin)

In addition to pills and capsules, powders, liquids, and teas are all forms of diet supplements that can be used orally. A meal isn’t required for all goods; some can be taken on their own. Your metabolism, your body’s system for converting food into energy, is reportedly stimulated by diet pills sold over the counter. Products like Dexatrim with Metabolic Support contain caffeine, a stimulant for the central nervous system that may aid in thermogenesis, the process of burning fat. These stimulants, however, may pose more of a risk than they are worth.

Weight Loss Supplements Sides Effects

There are several diet pills that are safe and may even help you lose weight, feel fuller, or increase your metabolism. However, the FDA has prohibited the use of popular weight loss components due to the following negative effects:

  • Heart rate rises
  • Blood pressure that is above normal.
  • Agitation
  • Diarrhea
  • Sleeplessness
  • Problems with the kidneys
  • Damage to the liver
  • Bleeding in the rectum

Obesity treatments for Weight Loss

There are a number of goods on this list that are considered natural cures or alternative therapies for obesity. Unlike the medications in the table above, their efficacy may not have been rigorously evaluated to the same extent. It’s possible that their use in the treatment of obesity has historical, cultural, or anecdotal evidence to back them up.

  • Garcinia Cambogia
  • Guarana
  • Hoodia
  • Ephedra

Frequently Asked Questions

Do I have to go to a gym to lose weight?

Rapid weight loss can be achieved by Zumba, aerobics, and swimming, among other methods. Organize your meals: Try to come up with a 7-day meal plan. There should be a separate meal plan for morning, lunch, and dinner. This may help you keep to a healthy diet and avoid eating bad items.

Weight loss: Is eating rice good?

To summarize, white rice appears to have no effect on weight loss, either positively or negatively. There has been greater evidence, however, that diets heavy in whole grains like brown rice can aid weight loss as well as help people maintain a healthy body weight.

Is it true that drinking lemon water might help you lose weight?

Lemon water can help you feel full, stay hydrated, enhance your metabolism, and help you lose weight. Because of this, lemon water does nothing to help you lose weight.

Is there a particular activity that burns the most abdominal fat?

Crunches are the best way to get rid of abdominal fat. When it comes to fat-burning workouts, crunches are at the top of the list. With your knees bent and feet firmly on the ground, you can begin by lying down on your back.

Does drinking milk help you shed pounds?

Milk will not cause you to gain weight, and in fact, it can help you shed some of the pounds you’ve gained. Foods high in protein are essential for muscle formation and growth, and milk is one of the best sources. Additionally, it contains zinc, magnesium, calcium, vitamin B12, and vitamin D, among other elements.

Is it possible to lessen the size of our breasts?

Breasts are primarily composed of adipose tissue (fat), which is the primary component. A person’s breast size can be reduced by losing excess body fat. People can lose weight by exercising more and eating a nutritious diet. Breast tissue can be reduced by eating a low-calorie, high-nutrient diet.

Is it possible to lose weight by soaking in hot water?

Even if you’re just attempting to lose a few pounds, drinking a few glasses of hot or warm water each day may have additional benefits. In fact, a number of studies have found that drinking hot water can aid in weight loss and help you lose weight.

Is it okay to work out on an empty stomach?

Working out on an empty stomach isn’t going to harm you, and depending on your aim, it may even be beneficial. However, there are certain drawbacks to consider first. If you exercise before eating, you run the danger of “bonking,” a word used in sports to describe low blood sugar symptoms like fatigue or dizziness.

Is there a particular time of day when you should work out?

Afternoon workouts may give you an edge because you’ve already had a meal or two before getting started. This will help you burn fat and lose weight. Hackney explains that “blood sugar levels rise whenever you eat.” 2

Affiliate disclosure: The links contained in this product review may result in a small commission if you opt to purchase the product recommended at no additional cost to you. This goes towards supporting our research and editorial team and please know we only recommend high quality products.

Disclaimer: Please understand that any advice or guidelines revealed here are not even remotely a substitute for sound medical advice from a licensed healthcare provider. Make sure to consult with a professional physician before making any purchasing decision if you use medications or have concerns following the review details shared above. Individual results may vary as the statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure or prevent any disease.


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